(6-Chloro-4-(trifluoromethyl)pyridin-3-yl)boronic acid

(6-Chloro-4-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 1217500-87-2, is a halogenated pyridine boronic acid. Its molecular structure includes a pyridine ring substituted with a chlorine atom at position 6, a trifluoromethyl group at position 4, and a boronic acid group at position 3. With a molecular formula of C6H4BClF3NO2 and a molecular weight of 225.36, this compound serves as a key functionalized intermediate. It is widely employed in synthetic organic chemistry, especially in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling, to introduce substituted pyridine moieties into target molecules. This makes it valuable for the synthesis of pharmaceuticals, agrochemicals, and advanced materials in research and development.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.