Methyl 2-amino-2-(trifluoromethyl)but-3-ynoate

Methyl 2-amino-2-(trifluoromethyl)but-3-ynoate, with CAS 1262414-79-8, is an organic compound characterized by its unique combination of a trifluoromethyl group, an amino group, an ester functionality, and a terminal alkyne. This polyfunctional structure positions it as a valuable intermediate in the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research, where the incorporation of trifluoromethyl groups and diverse functionalities is often desired. Its alkyne moiety allows for click chemistry reactions and other alkyne-based transformations, while the amino and ester groups provide additional handles for further derivatization.

• Handle Methyl 2-amino-2-(trifluoromethyl)but-3-ynoate in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation of dust or vapors, and prevent skin and eye contact. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.