Ethyl 2-propyl-6-(trifluoromethyl)nicotinate

Ethyl 2-propyl-6-(trifluoromethyl)nicotinate, identified by CAS 1772822-98-6, is an organic chemical compound with the molecular formula C12H14F3NO2 and a molecular weight of 261.24 g/mol. It features a pyridine core substituted with an ethyl carboxylate group at position 3, a propyl group at position 2, and a trifluoromethyl group at position 6. This combination of functional groups makes it a versatile building block in synthetic organic chemistry. Its trifluoromethyl moiety can impart unique physicochemical properties, such as increased lipophilicity and metabolic stability, which are often desirable in drug discovery and agrochemical research. Researchers may utilize this compound in the synthesis of novel heterocyclic compounds, pharmaceutical intermediates, or as a scaffold for exploring structure-activity relationships in various biological systems.

• Handle Ethyl 2-propyl-6-(trifluoromethyl)nicotinate in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, rinse thoroughly with water. Consult the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures before use. Store in a cool, dry place, tightly sealed.