Chemical Identity
Molecular Formula
C6H4BF4NO2
Molecular Weight
208.91 g/mol
Exact Mass
209.027121
PubChem CID
121237361
IUPAC Name
[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]boronic acid
SMILES String
OB(O)c1ccnc(C(F)(F)F)c1F
Names & Synonyms
External Identifiers
Catalog Overview
3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acid (CAS 2096337-73-2) is a highly functionalized pyridine derivative featuring both a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a boronic acid functional group at the 4-position. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91, this compound serves as a key intermediate in the synthesis of complex organic molecules. The boronic acid group makes it particularly suitable for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds with diverse aryl or...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acid (CAS 2096337-73-2) is a highly functionalized pyridine derivative featuring both a fluorine atom and a trifluoromethyl group on the pyridine ring, along with a boronic acid functional group at the 4-position. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91, this compound serves as a key intermediate in the synthesis of complex organic molecules. The boronic acid group makes it particularly suitable for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds with diverse aryl or heteroaryl halides. The presence of fluorine and trifluoromethyl groups can impart unique electronic and steric properties to synthesized compounds, making this boronic acid valuable in medicinal chemistry and materials science research for developing novel compounds with enhanced biological activity or specific material properties. It is intended for Research Use Only (RUO).
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White crystalline powder
Physical State
Solid
Melting Point
209.0 °C
Boiling Point
317.0 °C
Density
1.55 g/cm³
Water Solubility
0.214 mol/L
Flash Point
170.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This product is for Research Use Only.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.