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(6-Bromo-5-(trifluoromethyl)pyridin-3-yl)boronic acid

CAS 2225176-89-4Formula C6H4BBrF3NO2MW 269.81PubChem 91882758

(6-Bromo-5-(trifluoromethyl)pyridin-3-yl)boronic acid is a brominated and trifluoromethylated pyridine boronic acid, serving as a versatile building block in organic synthesis, notably for Suzuki-Miyaura cross-coupling reactions in research applications.

Loading RDKit molecule structure...
InChIKey: QBFQUBLUXWZGDD-UHFFFAOYSA-NC6H4BBrF3NO2 | MW 269.81

Chemical Identity

Molecular Formula

C6H4BBrF3NO2

Molecular Weight

269.81 g/mol

Exact Mass

268.94706

PubChem CID

91882758

IUPAC Name

[6-bromo-5-(trifluoromethyl)-3-pyridinyl]boronic acid

SMILES String

OB(O)c1cnc(Br)c(C(F)(F)F)c1

Names & Synonyms

6-Bromo-5-trifluoromethylpyridine-3-boronic acid(6-Bromo-5-(trifluoromethyl)pyridin-3-yl)boronicacid
External Identifiers
CS-35006

Catalog Overview

(6-Bromo-5-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 2225176-89-4 and molecular formula C6H4BBrF3NO2, is a highly functionalized pyridine derivative. It incorporates a bromine atom, a trifluoromethyl group, and a boronic acid moiety on a pyridine ring. This combination of functional groups renders it a versatile intermediate in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. The boronic acid group facilitates various cross-coupling reactions, while the bromine and trifluoromethyl substituents impart specific electronic and steric properties...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

(6-Bromo-5-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 2225176-89-4 and molecular formula C6H4BBrF3NO2, is a highly functionalized pyridine derivative. It incorporates a bromine atom, a trifluoromethyl group, and a boronic acid moiety on a pyridine ring. This combination of functional groups renders it a versatile intermediate in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. The boronic acid group facilitates various cross-coupling reactions, while the bromine and trifluoromethyl substituents impart specific electronic and steric properties to the synthesized compounds. This product is intended for Research Use Only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white crystalline powder

Physical State

Solid

Melting Point

165.0 °C

Boiling Point

350.0 °C

Density

1.7 g/cm³

Water Solubility

Slightly soluble

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including chemical-resistant gloves, safety glasses or goggles, and a lab coat. Ensure use in a well-ventilated area or under a fume hood to prevent inhalation of dust or vapors. Avoid direct contact with skin and eyes. In case of exposure, rinse affected areas thoroughly with water and seek medical attention if irritation persists. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety and handling instructions.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

2-Bromo-6-(trifluoromethyl)pyridine-4-boronic acidCAS 2225170-30-7
5-Bromo-6-(trifluoromethyl)pyridin-3-ylboronic acidCAS 2225155-69-9
1688675-75-3CAS 1688675-75-3
5-Bromo-2-trifluoromethylpyridine-4-boronic acidCAS 1072951-57-5
2-Bromo-5-(trifluoromethyl)pyridine-3-boronic acidCAS 2377606-29-4

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293190GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.