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(-)-Carprofen

CAS 52263-83-9Formula C15H12ClNO2MW 273.71PubChem 6997572

(-)-Carprofen is the (R)-enantiomer of Carprofen, a known non-steroidal anti-inflammatory drug (NSAID). It is utilized in research to investigate stereoselective pharmacological activities, metabolic pathways, and structure-activity relationships, distinguishing its specific effects from the racemic mixture or the (S)-enantiomer.

Loading RDKit molecule structure...
InChIKey: PUXBGTOOZJQSKH-MRVPVSSYSA-NC15H12ClNO2 | MW 273.71

Chemical Identity

Molecular Formula

C15H12ClNO2

Molecular Weight

273.71 g/mol

Exact Mass

273.055656

PubChem CID

6997572

IUPAC Name

(2R)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid

SMILES String

C[C@@H](C(=O)O)c1ccc2c(c1)[nH]c1ccc(Cl)cc12

Names & Synonyms

(R)-Carprofen(R)-(-)-carprofen(R)-6-chloro-alpha-methylcarbazole-2-acetic acid(R)-2-(6-Chloro-9H-carbazol-2-yl)propanoic acid(R)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid
Show all synonyms
(R)-2-(6-chloro-9H-carbazol-2-yl)-propionic acidCHEBI:59206PUXBGTOOZJQSKH-MRVPVSSYSA-N(?R)-6-Chloro-?-methyl-9H-carbazole-2-acetic acidQ27126532(aR)-6-Chloro-a-methyl-9H-carbazole-2-acetic Acid; (-)-Carprofen; (R)-(-)-Carprofen; ; C 8011;UHG
External Identifiers
DTXSID40426422RefChem:1049090DTXCID70377256CHEMBL2171250SCHEMBL3910SCHEMBL29930903SCHEMBL30910956BDBM50397557FC19824PD132828CS-0529281NS00096937

Catalog Overview

(-)-Carprofen, identified by CAS 52263-83-9 and IUPAC name (2R)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, is the R-enantiomer of the non-steroidal anti-inflammatory drug (NSAID) Carprofen. This chiral compound is a valuable tool in research for exploring the stereospecificity of drug-receptor interactions, enzyme kinetics, and the distinct biological activities associated with its specific chirality. Its carbazole and propanoic acid structural motifs make it pertinent for medicinal chemistry investigations, particularly in elucidating structure-activity relationships among anti-inflammatory agents. Researchers may employ...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

(-)-Carprofen, identified by CAS 52263-83-9 and IUPAC name (2R)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, is the R-enantiomer of the non-steroidal anti-inflammatory drug (NSAID) Carprofen. This chiral compound is a valuable tool in research for exploring the stereospecificity of drug-receptor interactions, enzyme kinetics, and the distinct biological activities associated with its specific chirality. Its carbazole and propanoic acid structural motifs make it pertinent for medicinal chemistry investigations, particularly in elucidating structure-activity relationships among anti-inflammatory agents. Researchers may employ (-)-Carprofen to compare its efficacy, toxicity, and metabolic profile against its S-enantiomer or the racemic mixture in various in vitro and preclinical models.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

white crystalline powder

Physical State

solid

Melting Point

195.0 °C

Boiling Point

450.0 °C

Density

1.37 g/cm³

Water Solubility

5.75 × 10⁻⁵ mol/L

Flash Point

257.4 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle (-)-Carprofen with appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety glasses or goggles, and a lab coat. Work in a well-ventilated area or a chemical fume hood to prevent inhalation. Avoid direct contact with skin and eyes. In case of exposure, rinse affected areas thoroughly with water. Store the compound in a cool, dry place, securely sealed, and away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety guidelines before use. This product is for research use only and not intended for human or animal therapeutic applications.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

52263-47-5CAS 52263-47-5
52263-84-0CAS 52263-84-0
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Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 29189900GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.