4-Chloro-2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile

4-Chloro-2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile is a research-use chemical characterized by a chlorinated benzonitrile core substituted with a 5,5-dimethyl-1,3,2-dioxaborinane group, commonly known as a neopentyl glycol boronate ester. This compound serves as a versatile building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. Its structure makes it valuable for introducing both a cyano group and a chlorine atom into target molecules, facilitating further functionalization in complex synthetic routes.

• Handle 4-Chloro-2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including safety glasses, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, wash thoroughly with soap and water. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information and handling procedures before use.