5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is an organoboron compound characterized by a chlorobenzonitrile core substituted with a pinacol boronate ester at the ortho position to the nitrile group and a chlorine atom at the meta position. With a molecular formula of C13H15BClNO2 and a molecular weight of 263.53 g/mol, this compound serves as a key functionalized intermediate in synthetic chemistry. The pinacol boronate group is highly reactive in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the introduction of the substituted benzonitrile moiety into complex molecular structures. The nitrile group can be further transformed, and the chlorine atom provides another site for potential functionalization or substitution reactions. This makes it a valuable reagent for constructing diverse organic molecules, including potential pharmaceutical intermediates and materials science compounds, within a research-use context.

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