2-(2-Bromo-6-fluorophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione

2-(2-Bromo-6-fluorophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione, also known as 2-Bromo-6-fluorophenylboronic acid MIDA ester, is a valuable research chemical. It incorporates a 2-bromo-6-fluorophenyl moiety, which is an aryl group substituted with both bromine and fluorine, and a N-methyliminodiacetic acid (MIDA) boronate ester. MIDA esters are known for their enhanced stability, ease of handling, and compatibility with various reaction conditions compared to free boronic acids. This compound is primarily utilized in synthetic organic chemistry as a precursor for creating more complex molecules through carbon-carbon bond formation, especially in Suzuki-Miyaura cross-coupling reactions, where it can react with suitable electrophiles to form new aryl-aryl or aryl-heteroaryl bonds. Its unique substitution pattern makes it particularly useful for synthesizing fluorinated and brominated aromatic compounds relevant in medicinal chemistry and materials science.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.