1-Amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-1-carboxylic acid

1-Amino-5-(trifluoromethyl)-2,3-dihydro-1H-indene-1-carboxylic acid, with CAS number 1270462-50-4 and molecular formula C11H10F3NO2, is a chiral, trifluoromethylated indane derivative. It features an amino group and a carboxylic acid group at the C1 position of the indane ring, along with a trifluoromethyl group at the C5 position. This structure makes it a versatile intermediate for the synthesis of complex organic molecules, especially in medicinal chemistry and agrochemical research. Its trifluoromethyl group can impart unique physicochemical properties, such as increased lipophilicity and metabolic stability, to target compounds. The presence of both amine and carboxylic acid functionalities allows for diverse derivatization reactions, including amide bond formation, esterification, and salt formation, making it valuable for constructing novel chemical entities in drug discovery and materials science. This product is for Research Use Only (RUO).

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, tightly sealed, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information before use. This product is for Research Use Only.