4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-bis(trifluoromethyl)pyridine

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-bis(trifluoromethyl)pyridine, with CAS 1320747-32-7, is a highly functionalized pyridine derivative. It features a pinacol boronate ester at the 4-position and two electron-withdrawing trifluoromethyl groups at the 2 and 6 positions of the pyridine ring. This unique combination of functionalities makes it a valuable intermediate in various synthetic routes. The boronate ester moiety is particularly useful for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The trifluoromethyl groups can impart specific electronic and steric properties to target molecules, often enhancing metabolic stability or lipophilicity in drug discovery and agrochemical research. This compound is intended for Research Use Only (RUO).

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.