2-Amino-3,3,3-trifluoro-2-(3-fluorophenyl)propanoic acid

2-Amino-3,3,3-trifluoro-2-(3-fluorophenyl)propanoic acid, identified by CAS 1341562-07-9, is a chiral, non-proteinogenic amino acid derivative featuring a trifluoromethyl group and a fluorine atom on the phenyl ring. With a molecular formula of C9H7F4NO2 and a molecular weight of 237.15, this compound serves as a versatile functionalized intermediate. The presence of both an amino group and a carboxylic acid group, alongside the electron-withdrawing trifluoromethyl and fluoro substituents, provides diverse reactivity for further chemical transformations. It is particularly relevant in the synthesis of complex molecules where the incorporation of fluorine atoms is desired to modulate physicochemical properties, such as metabolic stability, lipophilicity, and binding affinity, in potential drug candidates or agrochemicals. Researchers may explore its use in peptide chemistry, asymmetric synthesis, or as a scaffold for novel compound libraries.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Refer to the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures. Store in a cool, dry place, away from incompatible materials.