tert-butyl N-(3-bromo-2,2-dimethylpropyl)carbamate

tert-butyl N-(3-bromo-2,2-dimethylpropyl)carbamate, with CAS number 1397707-56-0, is an organic compound characterized by a tert-butyl carbamate (Boc) protecting group on a primary amine and a bromine atom on a neopentyl-like carbon chain. This bifunctional nature makes it a valuable intermediate in synthetic chemistry. The Boc group offers protection for the amine functionality during multi-step syntheses, while the bromine atom serves as a reactive site for nucleophilic substitution, Grignard reactions, or palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings. Researchers can leverage this compound for the synthesis of complex molecules, including pharmaceuticals, agrochemicals, and materials, where precise control over functional group transformations is required. Its molecular formula is C10H20BrNO2 and its molecular weight is 266.18 g/mol.

• Handle tert-butyl N-(3-bromo-2,2-dimethylpropyl)carbamate in a well-ventilated fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat. Avoid inhalation, ingestion, and skin contact. In case of contact, wash thoroughly with soap and water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling precautions.