Tert-butyl (1-bromo-4-methylpentan-2-yl)carbamate

Tert-butyl (1-bromo-4-methylpentan-2-yl)carbamate, with CAS 142121-32-2 and molecular formula C11H22BrNO2, is a key functionalized intermediate in synthetic organic chemistry. This compound incorporates a tert-butyl carbamate (Boc) group, which serves as a robust protecting group for the amine functionality, alongside a reactive bromine atom. The presence of both a protected amine and a halogen makes it a versatile building block for constructing complex molecules. Researchers utilize this compound in various synthetic pathways, including nucleophilic substitution reactions, cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira after conversion to an organometallic species), and as a precursor for further derivatization. Its structure, featuring an isobutyl side chain, allows for the introduction of specific steric and electronic properties into target compounds. It is intended for research use only.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.