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2-Amino-4,4,5,5,5-pentafluoropentanoic acid

CAS 15959-97-4Formula C5H6F5NO2MW 207.1PubChem 22169541

2-Amino-4,4,5,5,5-pentafluoropentanoic acid is a fluorinated amino acid derivative, valuable as a building block in synthetic organic chemistry, particularly for introducing pentafluoropentyl groups into complex molecules. It is primarily used in research and development for synthesizing novel compounds with modified physicochemical properties.

Loading RDKit molecule structure...
InChIKey: WDXQGHPDMGJLFY-UHFFFAOYSA-NC5H6F5NO2 | MW 207.1

Chemical Identity

Molecular Formula

C5H6F5NO2

Molecular Weight

207.1 g/mol

Exact Mass

207.031869

PubChem CID

22169541

SMILES String

NC(CC(F)(F)C(F)(F)F)C(=O)O

Names & Synonyms

C5H6F5NO24,4,5,5,5-Pentafluoronorvaline2-amino-4,4,5,5,5-pentafluoro-pentanoic acid
External Identifiers
SCHEMBL890552DTXSID701305698AKOS012259535CS-0344474EN300-1297845

Catalog Overview

2-Amino-4,4,5,5,5-pentafluoropentanoic acid, with CAS 15959-97-4 and molecular formula C5H6F5NO2, is a unique functionalized intermediate featuring both an amino and a carboxylic acid group, alongside a pentafluoropentyl chain. This combination makes it a versatile reagent for various synthetic applications. The presence of five fluorine atoms can significantly influence the compound's electronic properties, lipophilicity, and metabolic stability, making it particularly interesting for drug discovery and materials science research. It serves as a chiral building block for the synthesis of fluorinated peptides, peptidomimetics, and...

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Read more catalog context

2-Amino-4,4,5,5,5-pentafluoropentanoic acid, with CAS 15959-97-4 and molecular formula C5H6F5NO2, is a unique functionalized intermediate featuring both an amino and a carboxylic acid group, alongside a pentafluoropentyl chain. This combination makes it a versatile reagent for various synthetic applications. The presence of five fluorine atoms can significantly influence the compound's electronic properties, lipophilicity, and metabolic stability, making it particularly interesting for drug discovery and materials science research. It serves as a chiral building block for the synthesis of fluorinated peptides, peptidomimetics, and other biologically active molecules, where the incorporation of fluorine can enhance target binding or improve pharmacokinetic profiles. Researchers utilize this compound in the development of new pharmaceuticals, agrochemicals, and specialty materials.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline solid or powder

Physical State

Solid

Melting Point

200.0 °C

Boiling Point

300.0 °C

Density

1.49 g/cm³

Water Solubility

Soluble

Flash Point

59.7 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

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