2-[4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile

2-[4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile is a meticulously synthesized organic compound with the chemical formula C14H17BFNO2 and a molecular weight of 261.10 g/mol. It incorporates a fluorinated phenyl ring, an acetonitrile group, and a boronic acid pinacol ester (Bpin) moiety. The Bpin group is highly valued in synthetic chemistry for its stability and reactivity in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. The presence of fluorine can impart unique electronic and steric properties, influencing reaction selectivity and the biological activity of derived compounds. This makes it a valuable intermediate for researchers engaged in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.

• Handle 2-[4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat. Avoid inhalation, ingestion, and skin contact. In case of contact, wash thoroughly with soap and water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling precautions.