tert-Butyl (2-bromoallyl)carbamate

tert-Butyl (2-bromoallyl)carbamate, identified by CAS 178313-98-9, is an organic compound with the molecular formula C8H14BrNO2 and a molecular weight of 236.11 g/mol. It incorporates a tert-butyl carbamate (Boc) protecting group on an amine, alongside a 2-bromoallyl group. This structural combination makes it a key intermediate in synthetic chemistry. The Boc group offers robust protection for the amine during multi-step syntheses, while the 2-bromoallyl unit provides a site for diverse chemical transformations, including palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki, Sonogashira) or nucleophilic displacement reactions. Researchers utilize this compound as a versatile building block for constructing complex molecules, particularly in the synthesis of pharmaceuticals, agrochemicals, and materials science applications, where precise control over amine and alkene functionalization is required.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures before use.