2-(1,1,2,2,2-Pentafluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

This compound is a valuable research-use chemical characterized by a pyridine core substituted with a pentafluoroethyl group and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) moiety. The pentafluoroethyl group introduces significant electronegativity and steric bulk, which can influence the physicochemical properties of derived compounds. The pinacol boronate ester is a highly reactive functional group, making this compound an excellent substrate for various cross-coupling reactions, such as Suzuki-Miyaura coupling, to form new carbon-carbon bonds. Its unique combination of a fluorinated pyridine and a boronate ester makes it particularly useful in the synthesis of novel fluorinated heterocycles for medicinal chemistry, agrochemistry, and materials science research.

• Handle with appropriate personal protective equipment, including safety glasses, gloves, and a lab coat. Use in a well-ventilated area or a chemical fume hood to avoid inhalation. Prevent skin and eye contact. In case of contact, rinse immediately with plenty of water. Avoid ingestion. Store in a cool, dry place, tightly sealed, and away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety information before handling.