tert-butyl N-(4-bromobutyl)-N-methylcarbamate

tert-butyl N-(4-bromobutyl)-N-methylcarbamate (CAS 188793-11-5) is an organic compound with the molecular formula C10H20BrNO2 and a molecular weight of 266.18 g/mol. It features a tert-butyl carbamate protecting group on a methylamine, which is further substituted with a 4-bromobutyl chain. This bifunctional nature makes it a valuable building block in synthetic chemistry. The bromoalkyl moiety can undergo various nucleophilic substitution reactions (e.g., with amines, thiols, or alcohols) or participate in metal-catalyzed cross-coupling reactions after conversion to a Grignard reagent or organolithium compound. The tert-butyl carbamate (Boc) group serves as a common protecting group for the nitrogen atom, which can be selectively deprotected under acidic conditions to yield the free secondary amine. This compound is typically employed in the synthesis of more complex molecules, including pharmaceuticals, agrochemicals, and materials science research.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. May cause irritation to skin, eyes, and respiratory tract. Refer to the Safety Data Sheet (SDS) for detailed hazard information and emergency procedures. Store in a cool, dry place, away from incompatible materials.