Chemical Identity
Molecular Formula
C13H17BF3NO2
Molecular Weight
287.09 g/mol
Exact Mass
287.130443
PubChem CID
129946716
IUPAC Name
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(2,2,2-trifluoroethyl)pyridine
SMILES String
CC1(C)OB(c2cncc(CC(F)(F)F)c2)OC1(C)C
Names & Synonyms
External Identifiers
Catalog Overview
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(2,2,2-trifluoroethyl)pyridine is a meticulously designed organic compound for research applications. It incorporates a pyridine core substituted with a pinacol boronate ester at position 3 and a 2,2,2-trifluoroethyl group at position 5. The boronate ester functionality makes it an excellent precursor for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The trifluoroethyl moiety introduces fluorine atoms, which can impart unique electronic properties, enhance metabolic stability, or modify lipophilicity in target...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(2,2,2-trifluoroethyl)pyridine is a meticulously designed organic compound for research applications. It incorporates a pyridine core substituted with a pinacol boronate ester at position 3 and a 2,2,2-trifluoroethyl group at position 5. The boronate ester functionality makes it an excellent precursor for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The trifluoroethyl moiety introduces fluorine atoms, which can impart unique electronic properties, enhance metabolic stability, or modify lipophilicity in target molecules, making this compound valuable in medicinal chemistry and materials science research.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white crystalline solid
Physical State
Solid
Melting Point
123.0 °C
Boiling Point
281.0 °C
Density
1.4 g/cm³
Water Solubility
6.92 × 10⁻⁴ mol/L
Flash Point
187.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related products and analog discovery will be available as catalog graph data is expanded.