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2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine

CAS 1971914-58-5Formula C12H14BF4NO2MW 291.05PubChem 129946537

This compound is a fluorinated pyridine derivative featuring a pinacol boronate group and a trifluoromethyl substituent. It serves as a versatile building block in organic synthesis, particularly for creating complex molecules through cross-coupling reactions, and is intended for Research Use Only.

Loading RDKit molecule structure...
InChIKey: XUEWHDZTSUZPCG-UHFFFAOYSA-NC12H14BF4NO2 | MW 291.05

Chemical Identity

Molecular Formula

C12H14BF4NO2

Molecular Weight

291.05 g/mol

Exact Mass

291.105372

PubChem CID

129946537

SMILES String

CC1(C)OB(c2cnc(F)c(C(F)(F)F)c2)OC1(C)C

Names & Synonyms

2-fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridineZ20497677986-Fluoro-5-trifluoromethylpyridine-3-boronic acid pinacol ester
External Identifiers
CS-32673EN300-12600138

Catalog Overview

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine, identified by CAS 1971914-58-5, is a highly functionalized pyridine derivative. Its molecular structure features a fluorine atom, a trifluoromethyl group, and a pinacol boronate ester strategically positioned on the pyridine ring. This combination of functional groups renders it a valuable intermediate in various research and development applications. The pinacol boronate moiety is particularly adept for Suzuki-Miyaura cross-coupling reactions, facilitating the formation of new carbon-carbon bonds with aryl or heteroaryl halides.

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Read more catalog context

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine, identified by CAS 1971914-58-5, is a highly functionalized pyridine derivative. Its molecular structure features a fluorine atom, a trifluoromethyl group, and a pinacol boronate ester strategically positioned on the pyridine ring. This combination of functional groups renders it a valuable intermediate in various research and development applications. The pinacol boronate moiety is particularly adept for Suzuki-Miyaura cross-coupling reactions, facilitating the formation of new carbon-carbon bonds with aryl or heteroaryl halides. The trifluoromethyl group often confers distinct electronic and steric properties, which can influence the reactivity and potential biological activity of synthesized target molecules. This compound is strictly for Research Use Only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White solid

Physical State

Solid

Melting Point

95.0 °C

Boiling Point

300.0 °C

Density

1.4 g/cm³

Water Solubility

Slightly soluble

Flash Point

170.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including chemical-resistant gloves, safety glasses or goggles, and a lab coat. Ensure use in a well-ventilated area or a certified chemical fume hood to prevent inhalation exposure. Avoid direct contact with skin and eyes. In the event of contact, immediately flush the affected area with copious amounts of water. Store the compound in a cool, dry place, securely sealed and away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for comprehensive safety guidelines and emergency procedures prior to handling. This product is intended solely for research purposes and is not for human or animal therapeutic, diagnostic, or clinical use.

Related Products / Graph Discovery

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