Chemical Identity
Molecular Formula
C12H14BF4NO2
Molecular Weight
291.05 g/mol
Exact Mass
291.105372
PubChem CID
123860100
IUPAC Name
3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine
SMILES String
CC1(C)OB(c2cnc(C(F)(F)F)c(F)c2)OC1(C)C
Names & Synonyms
External Identifiers
Catalog Overview
3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine is a highly functionalized pyridine intermediate. It incorporates a fluorine atom, a trifluoromethyl group, and a pinacol boronate ester moiety. The boronate ester group makes it an excellent reagent for carbon-carbon bond formation, such as in Suzuki-Miyaura coupling reactions, enabling the introduction of the fluorinated pyridine scaffold into more complex molecular structures. The trifluoromethyl group often imparts unique electronic and steric properties, which can be beneficial in medicinal chemistry and material science research.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine is a highly functionalized pyridine intermediate. It incorporates a fluorine atom, a trifluoromethyl group, and a pinacol boronate ester moiety. The boronate ester group makes it an excellent reagent for carbon-carbon bond formation, such as in Suzuki-Miyaura coupling reactions, enabling the introduction of the fluorinated pyridine scaffold into more complex molecular structures. The trifluoromethyl group often imparts unique electronic and steric properties, which can be beneficial in medicinal chemistry and material science research. This compound is valuable for researchers synthesizing novel fluorinated compounds.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white solid
Physical State
solid
Melting Point
97.0 °C
Boiling Point
242.0 °C
Density
1.4 g/cm³
Water Solubility
6.03 × 10⁻⁴ mol/L
Flash Point
115.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood. Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, tightly sealed.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related products and analog discovery will be available as catalog graph data is expanded.