3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine

3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, identified by CAS 2121511-95-1, is a sophisticated organic compound with the molecular formula C13H17BF3NO2 and a molecular weight of 287.09 g/mol. It incorporates a trifluoromethyl group, a methyl group, and a pinacol boronic ester moiety on a pyridine core. The pinacol boronic ester functionality makes it highly reactive in various palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group often imparts unique electronic properties and metabolic stability to target molecules, making this compound valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. It serves as a key intermediate for introducing substituted pyridine rings into more complex molecular architectures for research purposes.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use in a research setting.