tert-Butyl (2-bromoethyl)(prop-2-yn-1-yl)carbamate

tert-Butyl (2-bromoethyl)(prop-2-yn-1-yl)carbamate, with CAS number 2142567-32-4 and molecular formula C10H16BrNO2, is a valuable chemical intermediate for research purposes. It incorporates three key reactive functionalities: a tert-butyl carbamate (Boc) group for amine protection, a bromoethyl group serving as an electrophile for alkylation reactions, and a terminal alkyne (propargyl) group, which is highly amenable to 'click chemistry' reactions such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). Researchers can utilize this compound in multi-step synthetic routes to introduce protected amines, alkyl chains, and alkyne handles into target molecules, facilitating the construction of diverse chemical structures for drug discovery, materials science, and chemical biology studies. Its precise structure allows for controlled functionalization and diversification in complex synthetic pathways.

• Handle tert-Butyl (2-bromoethyl)(prop-2-yn-1-yl)carbamate in a well-ventilated fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, wash thoroughly with soap and water. Consult the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures before use. Store in a cool, dry place, away from incompatible materials.