2-Trifluoromethyl-4-(2-methylpiperidin-1-yl)phenylboronic acid

2-Trifluoromethyl-4-(2-methylpiperidin-1-yl)phenylboronic acid, identified by CAS 2225151-81-3, is an organic compound with the molecular formula C13H17BF3NO2 and a molecular weight of 287.09 g/mol. It features a phenylboronic acid core substituted with a trifluoromethyl group at position 2 and a 2-methylpiperidin-1-yl group at position 4. As a boronic acid, it is a versatile building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, which are widely used for forming carbon-carbon bonds. The presence of the trifluoromethyl group can impart unique electronic and steric properties, potentially influencing reactivity and biological activity in derived compounds. The piperidine moiety adds further structural complexity and potential for diverse chemical modifications. This compound is suitable for use as a chemical intermediate in various research and development projects.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.