Chemical Identity
Molecular Formula
C9H9BF3NO2
Molecular Weight
230.98 g/mol
Exact Mass
231.067843
PubChem CID
133554662
IUPAC Name
[2-cyclopropyl-5-(trifluoromethyl)-3-pyridinyl]boronic acid
SMILES String
OB(O)c1cc(C(F)(F)F)cnc1C1CC1
Names & Synonyms
External Identifiers
Catalog Overview
(2-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 2225176-76-9, is a sophisticated pyridine derivative. This compound features a boronic acid moiety, a cyclopropyl ring, and a trifluoromethyl group, making it a highly versatile and reactive intermediate for advanced organic synthesis. Its boronic acid functionality is particularly useful for forming new carbon-carbon bonds through cross-coupling reactions, such as the Suzuki-Miyaura coupling. The trifluoromethyl group can introduce specific electronic and steric properties, often beneficial for enhancing metabolic stability or lipophilicity in...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
(2-Cyclopropyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 2225176-76-9, is a sophisticated pyridine derivative. This compound features a boronic acid moiety, a cyclopropyl ring, and a trifluoromethyl group, making it a highly versatile and reactive intermediate for advanced organic synthesis. Its boronic acid functionality is particularly useful for forming new carbon-carbon bonds through cross-coupling reactions, such as the Suzuki-Miyaura coupling. The trifluoromethyl group can introduce specific electronic and steric properties, often beneficial for enhancing metabolic stability or lipophilicity in synthesized target molecules. The cyclopropyl group contributes to structural rigidity and can influence molecular conformation. This chemical is intended for research applications requiring complex synthetic building blocks.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white crystalline solid
Physical State
Solid
Melting Point
145.0 °C
Density
1.35 g/cm³
Water Solubility
Slightly soluble
Flash Point
160.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE), including chemical-resistant gloves, eye protection, and a lab coat. Use in a well-ventilated area or a fume hood to prevent inhalation. Avoid direct contact with skin and eyes. In case of exposure, rinse affected areas immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive hazard information and detailed safe handling procedures. This product is for Research Use Only (RUO).
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
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