Chemical Identity
Molecular Formula
C6H4BF3INO2
Molecular Weight
316.81 g/mol
Exact Mass
316.93319
PubChem CID
133634711
IUPAC Name
[2-iodo-6-(trifluoromethyl)-4-pyridinyl]boronic acid
SMILES String
OB(O)c1cc(I)nc(C(F)(F)F)c1
Names & Synonyms
External Identifiers
Catalog Overview
(2-Iodo-6-(trifluoromethyl)pyridin-4-yl)boronic acid is a highly functionalized pyridine derivative featuring both a boronic acid group and an iodine substituent, alongside a trifluoromethyl group. This compound serves as a valuable intermediate in synthetic organic chemistry, enabling diverse transformations. The boronic acid moiety is particularly amenable to Suzuki-Miyaura cross-coupling reactions, allowing for the formation of new carbon-carbon bonds with aryl or vinyl halides. The iodine atom can also participate in various coupling reactions or be further functionalized.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
(2-Iodo-6-(trifluoromethyl)pyridin-4-yl)boronic acid is a highly functionalized pyridine derivative featuring both a boronic acid group and an iodine substituent, alongside a trifluoromethyl group. This compound serves as a valuable intermediate in synthetic organic chemistry, enabling diverse transformations. The boronic acid moiety is particularly amenable to Suzuki-Miyaura cross-coupling reactions, allowing for the formation of new carbon-carbon bonds with aryl or vinyl halides. The iodine atom can also participate in various coupling reactions or be further functionalized. The trifluoromethyl group introduces strong electron-withdrawing properties and increased lipophilicity, which can be beneficial in designing novel compounds with specific physicochemical properties. It is intended for Research Use Only (RUO).
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white solid
Physical State
Solid
Melting Point
180.0 °C
Boiling Point
350.0 °C
Density
1.7 g/cm³
Water Solubility
Slightly soluble
Flash Point
180.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood. Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place away from incompatible materials.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related products and analog discovery will be available as catalog graph data is expanded.