Chemical Identity
Molecular Formula
C8H4F4O3
Molecular Weight
224.11 g/mol
Exact Mass
224.009657
PubChem CID
952397
SMILES String
COc1c(F)c(F)c(C(=O)O)c(F)c1F
Names & Synonyms
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External Identifiers
Catalog Overview
2,3,5,6-Tetrafluoro-4-methoxybenzoic acid (CAS 3153-01-3) is an organic compound featuring a benzoic acid core substituted with four fluorine atoms and a methoxy group. Its molecular formula is C8H4F4O3 and its molecular weight is 224. 11 g/mol. This highly fluorinated aromatic carboxylic acid serves as a versatile functionalized intermediate in various research applications, especially in the synthesis of novel fluorinated molecules for medicinal chemistry, agrochemicals, and materials science.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
2,3,5,6-Tetrafluoro-4-methoxybenzoic acid (CAS 3153-01-3) is an organic compound featuring a benzoic acid core substituted with four fluorine atoms and a methoxy group. Its molecular formula is C8H4F4O3 and its molecular weight is 224.11 g/mol. This highly fluorinated aromatic carboxylic acid serves as a versatile functionalized intermediate in various research applications, especially in the synthesis of novel fluorinated molecules for medicinal chemistry, agrochemicals, and materials science. The presence of multiple fluorine atoms imparts unique electronic and steric properties, making it valuable for modifying compound lipophilicity, metabolic stability, and binding affinity in drug discovery efforts.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White solid
Physical State
Solid
Melting Point
125.0 °C
Boiling Point
248.0 °C
Density
1.54 g/cm³
Water Solubility
Slightly soluble
Flash Point
97.2 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.
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