3-Bromo-2-cyanophenylboronic acid neopentyl glycol ester

3-Bromo-2-cyanophenylboronic acid neopentyl glycol ester, identified by CAS 883899-07-8, is a meticulously synthesized chemical intermediate with the molecular formula C12H13BBrNO2 and a molecular weight of 293.95. This compound incorporates a bromine atom and a cyano group on a phenyl ring, alongside a neopentyl glycol boronic ester functionality. The boronic ester group is a key feature, enabling its participation in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, a fundamental tool in modern organic chemistry for forming carbon-carbon bonds. The bromine atom also offers an additional site for further functionalization through various coupling reactions or nucleophilic substitutions. The cyano group can be transformed into other functionalities, such as carboxylic acids or amines, expanding its synthetic utility. This compound is valuable for researchers engaged in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, serving as a crucial building block for creating diverse chemical structures in a research-use-only context.

• Handle 3-Bromo-2-cyanophenylboronic acid neopentyl glycol ester in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including safety goggles, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.