2-(4-Iodophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione

2-(4-Iodophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione, also known as 4-Iodophenylboronic acid MIDA ester, is a protected form of 4-iodophenylboronic acid. MIDA (N-methyliminodiacetic acid) esters are highly valued in organic synthesis for their enhanced stability, crystallinity, and air-stability compared to free boronic acids, making them convenient and robust reagents. The presence of the iodine atom at the para-position of the phenyl ring provides a reactive site for palladium-catalyzed cross-coupling reactions, particularly Suzuki-Miyaura couplings, enabling the efficient formation of new carbon-carbon bonds. This compound serves as a versatile building block in medicinal chemistry, agrochemical research, and materials science for synthesizing complex molecules and advanced intermediates.

• Handle with appropriate personal protective equipment, including chemical-resistant gloves, eye protection, and a lab coat. Use in a well-ventilated area or a certified fume hood to minimize exposure to dust or vapors. Avoid inhalation, ingestion, and contact with skin and eyes. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information, first-aid measures, and safe handling and storage procedures. Store in a cool, dry place, away from incompatible materials.