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2-amino-3-[2-fluoro-3-(trifluoromethyl)phenyl]propanoic Acid

CAS 1259993-82-2Formula C10H9F4NO2MW 251.18PubChem 3815160

This is a fluorinated phenylalanine derivative, often used in medicinal chemistry and drug discovery as a building block or a probe. Its trifluoromethyl and fluoro substituents can influence its pharmacokinetic and pharmacodynamic properties.

Loading RDKit molecule structure...
InChIKey: CMTKGTLWCOCZOE-UHFFFAOYSA-NC10H9F4NO2 | MW 251.18

Chemical Identity

Molecular Formula

C10H9F4NO2

Molecular Weight

251.18 g/mol

Exact Mass

251.056941

PubChem CID

3815160

SMILES String

NC(Cc1cccc(C(F)(F)F)c1F)C(=O)O

Names & Synonyms

2-FLUORO-3-(TRIFLUOROMETHYL)-DL-PHENYLALANINE2-Amino-3-(2-fluoro-3-(trifluoromethyl)phenyl)propanoic acid2-Fluoro-3-(trifluoromethyl)-DL-phenylalanine (H-DL-Phe(2-F,3-CF3)-OH)2-Fluoro-3-(trifluoromethyl)phenylalanine
External Identifiers
MFCD04116000SBB100915AKOS015956612CS-0268613EN300-1932605

Catalog Overview

2-amino-3-[2-fluoro-3-(trifluoromethyl)phenyl]propanoic Acid, also known as 2-Fluoro-3-(trifluoromethyl)-DL-phenylalanine, is a synthetic amino acid derivative. It features a phenyl ring substituted with both a fluorine atom and a trifluoromethyl group, along with a standard alanine backbone. This unique substitution pattern makes it a valuable compound in the synthesis of complex molecules, particularly in pharmaceutical research where fluorine and trifluoromethyl groups are often incorporated to enhance metabolic stability, lipophilicity, and binding affinity of potential drug candidates. It is typically supplied for research...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

2-amino-3-[2-fluoro-3-(trifluoromethyl)phenyl]propanoic Acid, also known as 2-Fluoro-3-(trifluoromethyl)-DL-phenylalanine, is a synthetic amino acid derivative. It features a phenyl ring substituted with both a fluorine atom and a trifluoromethyl group, along with a standard alanine backbone. This unique substitution pattern makes it a valuable compound in the synthesis of complex molecules, particularly in pharmaceutical research where fluorine and trifluoromethyl groups are often incorporated to enhance metabolic stability, lipophilicity, and binding affinity of potential drug candidates. It is typically supplied for research and development purposes.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline solid or powder

Physical State

Solid

Melting Point

200.0 °C

Boiling Point

350.0 °C

Density

1.45 g/cm³

Water Solubility

Slightly soluble

Flash Point

270.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use. This product is for research use only and not for human or animal therapeutic or diagnostic use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

2,2,2-trifluoroethyl N-(5-fluoro-2-methylphenyl)carbamateCAS 1087788-89-3
2,2,2-trifluoroethyl N-(3-fluoro-4-methylphenyl)carbamateCAS 1087798-07-9
2-amino-3-[2-fluoro-4-(trifluoromethyl)phenyl]propanoic AcidCAS 439587-15-2
2,2,2-trifluoroethyl N-(2-fluoro-5-methylphenyl)carbamateCAS 1087797-87-2
2,2,2-trifluoroethyl N-(2-fluoro-4-methylphenyl)carbamateCAS 1087788-97-3

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292249GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.