2-Amino-3-methyl-2-(trifluoromethyl)butanoic acid

2-Amino-3-methyl-2-(trifluoromethyl)butanoic acid, with CAS 127048-24-2, is a chiral, non-natural amino acid featuring a trifluoromethyl group at the alpha-carbon. Its unique structure makes it a versatile synthetic intermediate, particularly in the development of novel pharmaceuticals and agrochemicals. The trifluoromethyl group can impart enhanced metabolic stability, lipophilicity, and binding affinity to molecules, while the amino acid moiety allows for incorporation into peptides or other complex structures. This compound is primarily utilized in research and development for the synthesis of fluorinated analogs of biologically active compounds.

• Handle 2-Amino-3-methyl-2-(trifluoromethyl)butanoic acid in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, away from incompatible materials.