(2-Bromoethyl)-ethylcarbamic acid tert-butyl ester

tert-Butyl N-(2-bromoethyl)-N-ethylcarbamate, also known as (2-Bromoethyl)-ethylcarbamic acid tert-butyl ester, is an organic compound with the molecular formula C9H18BrNO2 and a molecular weight of 252.15 g/mol. This compound combines a reactive bromoethyl group with an N-ethylcarbamate protected by a tert-butyl group. The bromoethyl functionality serves as an electrophilic site, enabling reactions such as nucleophilic substitutions to form new carbon-heteroatom or carbon-carbon bonds. The tert-butyl carbamate (Boc) group acts as a common protecting group for the nitrogen atom, which can be selectively deprotected under acidic conditions to reveal a secondary amine. This makes it a valuable intermediate in the synthesis of complex molecules, including pharmaceuticals and agrochemicals, where controlled introduction of ethylamino groups and subsequent functionalization are required.

• Handle tert-Butyl N-(2-bromoethyl)-N-ethylcarbamate in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation of dust or vapors, and prevent skin and eye contact. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for detailed safety information before use.