4-Chloro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)aniline

4-Chloro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)aniline is a sophisticated chemical building block with the molecular formula C13H16BClF3NO2. It incorporates a chloro substituent, a trifluoromethyl group, and a pinacol boronate ester on an aniline core. This combination of functional groups makes it a versatile reagent, particularly valuable in cross-coupling reactions like the Suzuki-Miyaura coupling, where the boronate ester can react with aryl halides or triflates to form new carbon-carbon bonds. The presence of the aniline group also allows for further derivatization, making it suitable for synthesizing complex organic molecules in pharmaceutical and agrochemical research.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling procedures.