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(R)-(2-Iodo-1-methyl-ethyl)-carbamic acid tert-butyl ester, 95%

CAS 446060-78-2Formula C8H16INO2MW 285.12PubChem 59077105

This is an (R)-enantiomer of a tert-butyl carbamate derivative featuring an iodo-substituted propyl chain. It serves as a chiral building block, primarily for research applications in organic synthesis, particularly in the preparation of more complex chiral molecules.

Loading RDKit molecule structure...
InChIKey: CUKVINMIOAQKNB-ZCFIWIBFSA-NC8H16INO2 | MW 285.12

Chemical Identity

Molecular Formula

C8H16INO2

Molecular Weight

285.12 g/mol

Exact Mass

285.02258

PubChem CID

59077105

IUPAC Name

tert-butyl N-[(2R)-1-iodopropan-2-yl]carbamate

SMILES String

C[C@H](CI)NC(=O)OC(C)(C)C

Names & Synonyms

824-856-7(R)-(2-Iodo-1-methyl-ethyl)-carbamic acid tert-butyl ester(R)-tert-Butyl (1-iodopropan-2-yl)carbamatetert-Butyl [(R)-2-iodo-1-methylethyl]carbamateC8H16INO2
Show all synonyms
tert-butyl (R)-(1-iodopropan-2-yl)carbamate(R)-N-Boc-1-iodo-2-propanamine(R)-tert-Butyl(1-iodopropan-2-yl)carbamateC78228tert-butyl N-[(1R)-2-iodo-1-methyl-ethyl]carbamate(R)-(2-Iodo-1-methyl-ethyl)-carbamic acid t-butyl ester
External Identifiers
RefChem:407075MFCD17171121SCHEMBL14124966BS-28746SY381978DB-257937CS-0212584

Catalog Overview

(R)-(2-Iodo-1-methyl-ethyl)-carbamic acid tert-butyl ester, with CAS 446060-78-2, is a chiral organoiodine compound. It incorporates a tert-butyl carbamate (Boc) protecting group on an amine, and an iodine atom on the adjacent carbon of a propyl chain, with an (R) stereochemistry at the methyl-substituted carbon. This compound is a valuable functionalized intermediate in synthetic organic chemistry. Its iodine functionality makes it suitable for various coupling reactions, nucleophilic substitutions, or as a precursor for other halogenated or functionalized derivatives.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

(R)-(2-Iodo-1-methyl-ethyl)-carbamic acid tert-butyl ester, with CAS 446060-78-2, is a chiral organoiodine compound. It incorporates a tert-butyl carbamate (Boc) protecting group on an amine, and an iodine atom on the adjacent carbon of a propyl chain, with an (R) stereochemistry at the methyl-substituted carbon. This compound is a valuable functionalized intermediate in synthetic organic chemistry. Its iodine functionality makes it suitable for various coupling reactions, nucleophilic substitutions, or as a precursor for other halogenated or functionalized derivatives. The Boc group provides amine protection, which can be selectively removed under acidic conditions, allowing for further derivatization of the amine. Its chiral nature makes it particularly useful in asymmetric synthesis for constructing stereochemically defined molecules. This chemical is intended for research use only.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

Colorless liquid

Physical State

Liquid

Melting Point

15.3 °C

Boiling Point

243.1 °C

Density

1.54 g/cm³

Water Solubility

1.34 × 10⁻³ mol/L

Flash Point

112.2 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

Tert-butyl (1-iodopropan-2-yl)carbamateCAS 363599-44-4
(S)-(2-Iodo-1-methyl-ethyl)-carbamic acid tert-butyl esterCAS 161529-20-0
tert-butyl N-(2-iodoethyl)-N-methylcarbamateCAS 918642-21-4
1-(Tert-butoxycarbonylamino)-2-iodopropaneCAS 220594-87-6
1909325-77-4CAS 1909325-77-4

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 290490GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.