MolGraphChemical Intelligence
Active Chemical RecordCatalog PreviewCatalog ready

2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

CAS 1451391-20-0Formula C12H15BF3NO2MW 273.06PubChem 74789434

2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a trifluorinated aniline derivative incorporating a pinacol boronic ester. This research-use chemical is a valuable intermediate for organic synthesis, particularly in palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds, enabling the creation of diverse fluorinated compounds.

Loading RDKit molecule structure...
InChIKey: ZWFBPKFAOYRZNJ-UHFFFAOYSA-NC12H15BF3NO2 | MW 273.06

Chemical Identity

Molecular Formula

C12H15BF3NO2

Molecular Weight

273.06 g/mol

Exact Mass

273.114793

PubChem CID

74789434

SMILES String

CC1(C)OB(c2cc(F)c(F)c(F)c2N)OC1(C)C

Names & Synonyms

2,3,4-trifluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline(2-Amino-3,4,5-trifluorophenyl)boronic acid pinacol esterF467251
External Identifiers
MFCD23713167SCHEMBL29469246AB92724CS-0175548

Catalog Overview

2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a highly fluorinated aromatic amine featuring a pinacol boronic ester group. This compound serves as a versatile building block in organic synthesis, particularly for the construction of complex molecules. The trifluorinated aniline moiety provides unique electronic and steric properties, while the boronic ester enables various cross-coupling reactions, such as Suzuki-Miyaura coupling, for C-C bond formation. It is intended for research use only.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white solid

Physical State

Solid

Melting Point

120.0 °C

Boiling Point

350.0 °C

Density

1.4 g/cm³

Water Solubility

Slightly soluble

Flash Point

200.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including chemical-resistant gloves, safety glasses or goggles, and a lab coat. Avoid inhalation of dust or vapors, and prevent skin or eye contact. In case of exposure, seek immediate medical attention. Store in a cool, dry place, away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for comprehensive safety information.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

3-(Piperidin-3-yl)-5-trifluoromethylphenylboronic acidCAS 2225152-66-7
2225177-59-1CAS 2225177-59-1
2-Trifluoromethylpyridine-5-boronic acid pinacol esterCAS 1218790-39-6
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridineCAS 1084953-47-8
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridineCAS 881402-16-0

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292149GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.