Active Chemical RecordCatalog PreviewCatalog ready

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine

CAS 1256482-62-8Formula C10H9ClF3NO2MW 267.63PubChem 46737694

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine is a halogenated phenylalanine derivative, characterized by a trifluoromethyl group and a chlorine atom on its phenyl ring. This racemic amino acid is primarily utilized in chemical synthesis as a building block, particularly in the development of novel pharmaceutical intermediates and research compounds.

Loading RDKit molecule structure...
InChIKey: HIWSTWSGMRXBSV-UHFFFAOYSA-NC10H9ClF3NO2 | MW 267.63

Chemical Identity

Molecular Formula

C10H9ClF3NO2

Molecular Weight

267.63 g/mol

Exact Mass

267.027391

PubChem CID

46737694

IUPAC Name

2-amino-3-[5-chloro-2-(trifluoromethyl)phenyl]propanoic acid

SMILES String

NC(Cc1cc(Cl)ccc1C(F)(F)F)C(=O)O

Names & Synonyms

2-Amino-3-(5-chloro-2-(trifluoromethyl)phenyl)propanoic acid5-Chloro-2-(trifluoromethyl)-DL-phenylalanine (H-DL-Phe(5-Cl,2-CF3)-OH)3-Chloro-6-(trifluoromethyl)phenylalaninePhenylalanine, 5-chloro-2-(trifluoromethyl)-2-Amino-3-(5-chloro-2-(trifluoromethyl)phenyl)propanoicacid
External Identifiers
MFCD09832385DTXSID701258374AKOS015957014

Catalog Overview

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine, with CAS number 1256482-62-8 and molecular formula C10H9ClF3NO2, is a synthetic amino acid derivative. It features a phenylalanine core substituted with a chlorine atom at the 5-position and a trifluoromethyl group at the 2-position of the phenyl ring. As a DL-phenylalanine, it represents a racemic mixture of the D- and L-enantiomers. Its unique halogenated and trifluoromethylated structure makes it a valuable chiral building block in organic synthesis, especially for creating complex molecules with potential biological activity.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine, with CAS number 1256482-62-8 and molecular formula C10H9ClF3NO2, is a synthetic amino acid derivative. It features a phenylalanine core substituted with a chlorine atom at the 5-position and a trifluoromethyl group at the 2-position of the phenyl ring. As a DL-phenylalanine, it represents a racemic mixture of the D- and L-enantiomers. Its unique halogenated and trifluoromethylated structure makes it a valuable chiral building block in organic synthesis, especially for creating complex molecules with potential biological activity. Researchers often employ such derivatives in medicinal chemistry for structure-activity relationship studies and the synthesis of drug-like compounds.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

white crystalline powder

Physical State

solid

Melting Point

200.0 °C

Boiling Point

380.0 °C

Density

1.4 g/cm³

Water Solubility

slightly soluble

Flash Point

153.9 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 5-Chloro-2-(trifluoromethyl)-DL-phenylalanine in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation of dust or vapors, and prevent skin and eye contact. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

2,2,2-trifluoroethyl N-(3-chloro-2-methylphenyl)carbamateCAS 1087797-97-4
3-Chloro-4-(trifluoromethyl)-DL-phenylalanineCAS 1259966-92-1
2,2,2-trifluoroethyl N-(3-chloro-4-methylphenyl)carbamateCAS 877964-35-7
2,2,2-trifluoroethyl N-(5-chloro-2-methylphenyl)carbamateCAS 1087788-56-4
2,2,2-trifluoroethyl N-(2-chloro-4-methylphenyl)carbamateCAS 1087798-35-3

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292249GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.