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4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine

CAS 1259997-93-7Formula C10H9F4NO2MW 251.18PubChem 66523475

4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine is a fluorinated phenylalanine derivative, often utilized in research as a building block for synthesizing more complex molecules. Its unique structural features, including a trifluoromethyl group and a fluorine atom on the phenyl ring, make it valuable in medicinal chemistry and drug discovery efforts, particularly for developing compounds with altered pharmacokinetic properties.

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InChIKey: NICCVNASMKOGPH-UHFFFAOYSA-NC10H9F4NO2 | MW 251.18

Chemical Identity

Molecular Formula

C10H9F4NO2

Molecular Weight

251.18 g/mol

Exact Mass

251.056941

PubChem CID

66523475

IUPAC Name

2-amino-3-[4-fluoro-2-(trifluoromethyl)phenyl]propanoic acid

SMILES String

NC(Cc1ccc(F)cc1C(F)(F)F)C(=O)O

Names & Synonyms

2-Amino-3-(4-fluoro-2-(trifluoromethyl)phenyl)propanoic acid4-Fluoro-2-trifluoromethyl-DL-phenylalanine2-Amino-3-(4-fluoro-2-(trifluoromethyl)phenyl)propanoicacid
External Identifiers
MFCD09914879AKOS015956994CS-0269264EN300-1937823

Catalog Overview

4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine, identified by CAS 1259997-93-7, is a synthetic amino acid derivative. It features a phenylalanine backbone substituted with a fluorine atom at the 4-position and a trifluoromethyl group at the 2-position on the phenyl ring. With a molecular formula of C10H9F4NO2 and a molecular weight of 251. 18, this compound is classified within the research-oriented chemical scaffold.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine, identified by CAS 1259997-93-7, is a synthetic amino acid derivative. It features a phenylalanine backbone substituted with a fluorine atom at the 4-position and a trifluoromethyl group at the 2-position on the phenyl ring. With a molecular formula of C10H9F4NO2 and a molecular weight of 251.18, this compound is classified within the research-oriented chemical scaffold. The incorporation of fluorine and trifluoromethyl groups is a common strategy in pharmaceutical research to enhance metabolic stability, lipophilicity, and binding affinity of potential drug candidates. As a DL-phenylalanine derivative, it represents a racemic mixture, offering versatility for various synthetic routes in academic and industrial research settings. It serves as a key intermediate in the synthesis of novel compounds for diverse research applications.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline powder

Physical State

Solid

Melting Point

210.0 °C

Boiling Point

380.0 °C

Density

1.45 g/cm³

Water Solubility

Soluble

Flash Point

250.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine in a well-ventilated area, preferably under a fume hood. Wear appropriate personal protective equipment, including safety glasses, gloves, and a lab coat, to prevent skin and eye contact. Avoid inhalation of dust or vapors. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292249GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.