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2-amino-3-[3-fluoro-4-(trifluoromethyl)phenyl]propanoic Acid

CAS 1215491-31-8Formula C10H9F4NO2MW 251.18PubChem 3859099

2-amino-3-[3-fluoro-4-(trifluoromethyl)phenyl]propanoic Acid is a fluorinated phenylalanine derivative. This synthetic amino acid analog is valuable in medicinal chemistry and biochemical research as a building block for synthesizing peptides and peptidomimetics, particularly for exploring structure-activity relationships due to its fluorine and trifluoromethyl substitutions.

Loading RDKit molecule structure...
InChIKey: IHAMHAXPNFCJJZ-UHFFFAOYSA-NC10H9F4NO2 | MW 251.18

Chemical Identity

Molecular Formula

C10H9F4NO2

Molecular Weight

251.18 g/mol

Exact Mass

251.056941

PubChem CID

3859099

SMILES String

NC(Cc1ccc(C(F)(F)F)c(F)c1)C(=O)O

Names & Synonyms

3-FLUORO-4-(TRIFLUOROMETHYL)-DL-PHENYLALANINE2-Amino-3-(3-fluoro-4-(trifluoromethyl)phenyl)propanoic acidIHAMHAXPNFCJJZ-UHFFFAOYSA-N3-Fluoro-4-(trifluoromethyl)-DL-phenylalanine (H-DL-Phe(3-F,4-CF3)-OH)3-fluoro-4-(trifluoromethyl)phenylalanine
Show all synonyms
2-Amino-3-(3-fluoro-4-(trifluoromethyl)phenyl)propanoicacid
External Identifiers
MFCD04115998SCHEMBL13205280DTXSID501271467SBB100912AKOS015956771CS-0268791EN300-1937557

Catalog Overview

2-amino-3-[3-fluoro-4-(trifluoromethyl)phenyl]propanoic Acid, also known as 3-Fluoro-4-(trifluoromethyl)-DL-phenylalanine, is a synthetic amino acid derivative. Its structure features a phenylalanine backbone substituted with a fluorine atom and a trifluoromethyl group on the phenyl ring. These halogen substitutions are commonly employed in pharmaceutical research to modify physicochemical properties, enhance metabolic stability, or alter receptor interactions. As a phenylalanine analog, it may serve as a building block for synthesizing peptides, peptidomimetics, or other complex organic molecules for various research...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

2-amino-3-[3-fluoro-4-(trifluoromethyl)phenyl]propanoic Acid, also known as 3-Fluoro-4-(trifluoromethyl)-DL-phenylalanine, is a synthetic amino acid derivative. Its structure features a phenylalanine backbone substituted with a fluorine atom and a trifluoromethyl group on the phenyl ring. These halogen substitutions are commonly employed in pharmaceutical research to modify physicochemical properties, enhance metabolic stability, or alter receptor interactions. As a phenylalanine analog, it may serve as a building block for synthesizing peptides, peptidomimetics, or other complex organic molecules for various research applications, particularly in areas exploring structure-activity relationships in biological systems.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline solid or powder

Physical State

Solid

Melting Point

220.0 °C

Boiling Point

380.0 °C

Density

1.38 g/cm³

Water Solubility

Sparingly soluble

Flash Point

162.2 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 2-amino-3-[3-fluoro-4-(trifluoromethyl)phenyl]propanoic Acid with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Refer to the Safety Data Sheet (SDS) for comprehensive safety information and emergency procedures. Store in a cool, dry place, away from incompatible materials.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292249GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.