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5-Chloro-2-(trifluoromethyl)-DL-phenylalanine

CAS 1256482-62-8Formula C10H9ClF3NO2MW 267.63PubChem 46737694

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine is a halogenated phenylalanine derivative, characterized by a trifluoromethyl group and a chlorine atom on its phenyl ring. This racemic amino acid is primarily utilized in chemical synthesis as a building block, particularly in the development of novel pharmaceutical intermediates and research compounds.

Loading RDKit molecule structure...
InChIKey: HIWSTWSGMRXBSV-UHFFFAOYSA-NC10H9ClF3NO2 | MW 267.63

Chemical Identity

Molecular Formula

C10H9ClF3NO2

Molecular Weight

267.63 g/mol

Exact Mass

267.027391

PubChem CID

46737694

IUPAC Name

2-amino-3-[5-chloro-2-(trifluoromethyl)phenyl]propanoic acid

SMILES String

NC(Cc1cc(Cl)ccc1C(F)(F)F)C(=O)O

Names & Synonyms

2-Amino-3-(5-chloro-2-(trifluoromethyl)phenyl)propanoic acid5-Chloro-2-(trifluoromethyl)-DL-phenylalanine (H-DL-Phe(5-Cl,2-CF3)-OH)3-Chloro-6-(trifluoromethyl)phenylalaninePhenylalanine, 5-chloro-2-(trifluoromethyl)-2-Amino-3-(5-chloro-2-(trifluoromethyl)phenyl)propanoicacid
External Identifiers
MFCD09832385DTXSID701258374AKOS015957014

Catalog Overview

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine, with CAS number 1256482-62-8 and molecular formula C10H9ClF3NO2, is a synthetic amino acid derivative. It features a phenylalanine core substituted with a chlorine atom at the 5-position and a trifluoromethyl group at the 2-position of the phenyl ring. As a DL-phenylalanine, it represents a racemic mixture of the D- and L-enantiomers. Its unique halogenated and trifluoromethylated structure makes it a valuable chiral building block in organic synthesis, especially for creating complex molecules with potential biological activity.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

5-Chloro-2-(trifluoromethyl)-DL-phenylalanine, with CAS number 1256482-62-8 and molecular formula C10H9ClF3NO2, is a synthetic amino acid derivative. It features a phenylalanine core substituted with a chlorine atom at the 5-position and a trifluoromethyl group at the 2-position of the phenyl ring. As a DL-phenylalanine, it represents a racemic mixture of the D- and L-enantiomers. Its unique halogenated and trifluoromethylated structure makes it a valuable chiral building block in organic synthesis, especially for creating complex molecules with potential biological activity. Researchers often employ such derivatives in medicinal chemistry for structure-activity relationship studies and the synthesis of drug-like compounds.

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

white crystalline powder

Physical State

solid

Melting Point

200.0 °C

Boiling Point

380.0 °C

Density

1.4 g/cm³

Water Solubility

slightly soluble

Flash Point

153.9 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 5-Chloro-2-(trifluoromethyl)-DL-phenylalanine in a well-ventilated area or fume hood. Wear appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid inhalation of dust or vapors, and prevent skin and eye contact. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 292249GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.