(2-Fluoro-4-(trifluoromethyl)pyridin-3-yl)boronic acid

(2-Fluoro-4-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 2819705-93-4, is an organoboron compound characterized by a pyridine core substituted with a fluorine atom, a trifluoromethyl group at positions 2 and 4 respectively, and a boronic acid moiety at position 3. With a molecular formula of C6H4BF4NO2 and a molecular weight of 208.91 g/mol, this compound serves as a key functionalized intermediate. Its boronic acid functionality makes it highly reactive in various palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The presence of fluorine and trifluoromethyl groups can impart unique electronic and steric properties, making it valuable for synthesizing novel pharmaceutical candidates, agrochemicals, and advanced materials in research settings.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.