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(5-Fluoro-2-(trifluoromethyl)pyridin-4-yl)boronic acid

CAS 2941501-48-8Formula C6H4BF4NO2MW 208.91PubChem 168944367

(5-Fluoro-2-(trifluoromethyl)pyridin-4-yl)boronic acid is a fluorinated pyridine derivative featuring a trifluoromethyl group and a boronic acid moiety. It serves as a versatile functionalized intermediate in organic synthesis, particularly for cross-coupling reactions.

Loading RDKit molecule structure...
InChIKey: IHHZWDYTJKILLH-UHFFFAOYSA-NC6H4BF4NO2 | MW 208.91

Chemical Identity

Molecular Formula

C6H4BF4NO2

Molecular Weight

208.91 g/mol

Exact Mass

209.027121

PubChem CID

168944367

IUPAC Name

[5-fluoro-2-(trifluoromethyl)-4-pyridinyl]boronic acid

SMILES String

OB(O)c1cc(C(F)(F)F)ncc1F

External Identifiers
SCHEMBL25272443SCHEMBL30486617

Catalog Overview

(5-Fluoro-2-(trifluoromethyl)pyridin-4-yl)boronic acid, identified by CAS 2941501-48-8 and molecular formula C6H4BF4NO2, is a highly functionalized pyridine boronic acid. It features a fluorine atom and a trifluoromethyl group on the pyridine ring, alongside a boronic acid moiety. This combination of functional groups makes it a versatile building block in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling, for the construction of complex organic molecules. Its unique substitution pattern can introduce specific electronic and steric properties into target compounds.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

(5-Fluoro-2-(trifluoromethyl)pyridin-4-yl)boronic acid, identified by CAS 2941501-48-8 and molecular formula C6H4BF4NO2, is a highly functionalized pyridine boronic acid. It features a fluorine atom and a trifluoromethyl group on the pyridine ring, alongside a boronic acid moiety. This combination of functional groups makes it a versatile building block in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling, for the construction of complex organic molecules. Its unique substitution pattern can introduce specific electronic and steric properties into target compounds. This product is intended for research use only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white solid

Physical State

Solid

Melting Point

145.0 °C

Boiling Point

270.0 °C

Density

1.5 g/cm³

Water Solubility

Slightly soluble

Flash Point

160.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) for comprehensive safety information before use. This product is for research use only and not for human or animal therapeutic or diagnostic use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Similar products (text references)

2-Fluoro-5-(trifluoromethyl)pyridin-3-ylboronic acidCAS 1253569-51-5
[6-Fluoro-5-(trifluoromethyl)pyridin-3-yl]boronic acidCAS 2225175-78-8
1150114-63-8CAS 1150114-63-8
[6-Fluoro-2-(trifluoromethyl)pyridin-3-yl]boronic acidCAS 2096339-79-4
3-Fluoro-2-(trifluoromethyl)pyridine-4-boronic acidCAS 2096337-73-2

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 29333990GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.