Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate

Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamate, with CAS 1002310-00-0, is a sophisticated organic intermediate. Its structure incorporates a tert-butyl carbamate (Boc) protecting group on an ethylamine, a chloro substituent on the phenyl ring, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) group. This combination makes it highly valuable in synthetic chemistry, especially for palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura coupling, where the boronate ester acts as a nucleophilic coupling partner. The Boc group allows for selective deprotection of the amine, enabling further functionalization. Researchers utilize this compound as a key intermediate for the synthesis of pharmaceuticals, agrochemicals, and advanced materials for research-use applications.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and handling procedures.