3-Chloro-4-methoxy-5-(trifluoromethyl)benzoic acid

3-Chloro-4-methoxy-5-(trifluoromethyl)benzoic acid (CAS 1272528-86-5) is an organic compound with the molecular formula C9H6ClF3O3 and a molecular weight of 254.59 g/mol. It is characterized by a benzoic acid core substituted with a chlorine atom at position 3, a methoxy group at position 4, and a trifluoromethyl group at position 5. This combination of functional groups makes it a versatile intermediate in organic synthesis. Given its structural features, it is classified within the research-oriented chemical scaffold, suggesting its potential utility in medicinal chemistry research for the development of new pharmaceutical candidates or as a probe in biological studies. Researchers may explore its reactivity in various synthetic transformations, including esterification, amide formation, or further derivatization of the aromatic ring.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.