Chemical Identity
Molecular Formula
C14H15BF3NO2
Molecular Weight
297.08 g/mol
Exact Mass
297.114793
PubChem CID
59535276
SMILES String
CC1(C)OB(c2ccc(C(F)(F)F)c(C#N)c2)OC1(C)C
Names & Synonyms
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External Identifiers
Catalog Overview
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzonitrile, with CAS 1220219-14-6, is a sophisticated organic compound designed for research and development applications. It combines a trifluoromethyl group, a nitrile group, and a pinacol boronic ester on a benzene ring. The pinacol boronic ester functionality makes it an excellent reagent for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group often imparts unique electronic and steric properties, influencing reactivity and biological activity in...
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- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzonitrile, with CAS 1220219-14-6, is a sophisticated organic compound designed for research and development applications. It combines a trifluoromethyl group, a nitrile group, and a pinacol boronic ester on a benzene ring. The pinacol boronic ester functionality makes it an excellent reagent for palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The trifluoromethyl group often imparts unique electronic and steric properties, influencing reactivity and biological activity in synthesized molecules. The nitrile group can serve as a precursor for various other functional groups or participate in further synthetic transformations. This compound is valuable for synthesizing complex organic molecules, including potential pharmaceutical intermediates and materials science compounds.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white crystalline solid
Physical State
solid
Melting Point
119.0 °C
Boiling Point
289.0 °C
Density
1.45 g/cm³
Water Solubility
5.01 × 10⁻⁵ mol/L
Flash Point
165.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse thoroughly with water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This product is for research use only and not for human or animal therapeutic or diagnostic use.
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