4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-3-(trifluoromethyl)aniline

This compound, also known as 4-Amino-2-(trifluoromethyl)phenylboronic Acid Pinacol Ester, is a key functionalized intermediate for research applications. It combines an aniline moiety, a trifluoromethyl group, and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronic ester) group on a benzene ring. The pinacol boronic ester is a robust and widely utilized functional group in Suzuki-Miyaura cross-coupling reactions, allowing for the formation of new carbon-carbon bonds with aryl or vinyl halides. The trifluoromethyl group is known for its strong electron-withdrawing properties and metabolic stability, making it valuable in drug discovery and agrochemical research. The aniline group provides a site for further derivatization, such as acylation, alkylation, or diazotization. This chemical is intended for Research Use Only (RUO).

• Handle with appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat. Use in a well-ventilated area or a chemical fume hood to avoid inhalation. Prevent skin and eye contact. Do not ingest. Store in a cool, dry place, away from incompatible materials. Dispose of waste according to local regulations.