Active Chemical RecordCatalog PreviewCatalog ready

4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine

CAS 1612287-99-6Formula C13H17BF3NO2MW 287.09PubChem 90184892

This compound is a pyridine derivative featuring a trifluoromethyl group and a pinacol boronate ester. It serves as a versatile building block in organic synthesis, particularly for cross-coupling reactions, and is intended for Research Use Only (RUO).

Loading RDKit molecule structure...
InChIKey: NHTGGJIAIAPGHR-UHFFFAOYSA-NC13H17BF3NO2 | MW 287.09

Chemical Identity

Molecular Formula

C13H17BF3NO2

Molecular Weight

287.09 g/mol

Exact Mass

287.130443

PubChem CID

90184892

SMILES String

Cc1cc(C(F)(F)F)ncc1B1OC(C)(C)C(C)(C)O1

Names & Synonyms

2-(trifluoroMethyl)-4-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine(4-METHYL-6-(TRIFLUOROMETHYL)PYRIDIN-3-YL)BORONIC ACID PINACOL ESTER4-Methyl-6-trifluoromethylpyridine-3-boronic acid pinacol esterPyridine, 4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)-F472258
Show all synonyms
Z20499231124-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine
External Identifiers
MFCD18726737SCHEMBL15751070SCHEMBL31648713MPC28799AKOS027252254AS-41165DB-154278CS-0175838EN300-6498731

Catalog Overview

4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, with CAS 1612287-99-6, is a highly functionalized pyridine derivative. It incorporates a trifluoromethyl group, known for its strong electron-withdrawing properties, and a pinacol boronate ester moiety. The boronate ester makes this compound a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The pyridine core, along with the methyl and trifluoromethyl substituents, offers opportunities for synthesizing complex heterocyclic compounds with potential...

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow
Read more catalog context

4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine, with CAS 1612287-99-6, is a highly functionalized pyridine derivative. It incorporates a trifluoromethyl group, known for its strong electron-withdrawing properties, and a pinacol boronate ester moiety. The boronate ester makes this compound a valuable reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl or vinyl halides. The pyridine core, along with the methyl and trifluoromethyl substituents, offers opportunities for synthesizing complex heterocyclic compounds with potential applications in medicinal chemistry and materials science. This compound is intended for Research Use Only (RUO).

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White to off-white crystalline powder

Physical State

Solid

Melting Point

110.0 °C

Boiling Point

280.0 °C

Density

1.2 g/cm³

Water Solubility

Slightly soluble

Flash Point

135.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle with appropriate personal protective equipment (PPE) including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Recommended application cues

Research intermediateCustom synthesis building block

Catalog discovery cues, not supplier-verified claims.

Related HS Code / Compliance

HS Code: 293339GHS Pictograms: GHS07Shipment review: Shipment details require review before fulfillment.

Compliance cues are non-linked reference tags and require shipment review.

Catalog navigation

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.