3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)aniline

3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)aniline is an organic compound with the molecular formula C13H17BF3NO2 and a molecular weight of 287.09 g/mol. It incorporates a trifluoromethyl group (-CF3) and a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) moiety attached to an aniline benzene ring. The trifluoromethyl group is known for its electron-withdrawing properties and metabolic stability, while the pinacol boronate group is a versatile reagent for C-C bond formation, notably in Suzuki-Miyaura cross-coupling reactions. This compound serves as a valuable building block in the synthesis of various pharmaceutical intermediates and other fine chemicals, leveraging its reactive boronate and functionalized aromatic core.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for comprehensive safety information before use.