4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine-3-carbonitrile

4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine-3-carbonitrile, identified by CAS 2223042-76-8, is a meticulously designed organic intermediate. It incorporates a 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronate) group at the 4-position and a trifluoromethyl group at the 6-position of a pyridine-3-carbonitrile core. This unique combination of functional groups renders it highly valuable in various synthetic methodologies, particularly in Suzuki-Miyaura cross-coupling reactions for constructing complex molecular architectures. Its trifluoromethyl moiety can impart specific electronic and steric properties to target molecules, while the boronate ester serves as a robust handle for C-C bond formation. This compound is intended for research and development purposes only.

• Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed safety information before use.