Chemical Identity
Molecular Formula
C6H4BBrF3NO2
Molecular Weight
269.81 g/mol
Exact Mass
268.94706
PubChem CID
72212867
IUPAC Name
[2-bromo-6-(trifluoromethyl)-4-pyridinyl]boronic acid
SMILES String
OB(O)c1cc(Br)nc(C(F)(F)F)c1
Names & Synonyms
External Identifiers
Catalog Overview
2-Bromo-6-(trifluoromethyl)pyridine-4-boronic acid, with CAS number 2225170-30-7, is a highly functionalized pyridine derivative featuring a bromine atom, a trifluoromethyl group, and a boronic acid moiety. This unique combination of functional groups makes it a valuable intermediate in synthetic organic chemistry. The boronic acid group allows for facile participation in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The bromine atom provides another site for further functionalization, while the trifluoromethyl group can impart specific...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
2-Bromo-6-(trifluoromethyl)pyridine-4-boronic acid, with CAS number 2225170-30-7, is a highly functionalized pyridine derivative featuring a bromine atom, a trifluoromethyl group, and a boronic acid moiety. This unique combination of functional groups makes it a valuable intermediate in synthetic organic chemistry. The boronic acid group allows for facile participation in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, enabling the formation of new carbon-carbon bonds. The bromine atom provides another site for further functionalization, while the trifluoromethyl group can impart specific electronic and steric properties to the final molecule, often enhancing metabolic stability or lipophilicity. It is typically employed in the synthesis of pharmaceuticals, agrochemicals, and materials science research where complex pyridine structures are desired.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white solid
Physical State
Solid
Melting Point
165.0 °C
Boiling Point
320.0 °C
Density
1.8 g/cm³
Water Solubility
Slightly soluble
Flash Point
200.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle with appropriate personal protective equipment (PPE), including gloves, eye protection, and a lab coat. Work in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Refer to the Safety Data Sheet (SDS) for comprehensive safety information before handling. Dispose of chemical waste according to local regulations.
Related Products / Graph Discovery
Related products, derivatives, keywords, and application cues for catalog discovery.
Related CAS / Similar Products
Similar products (text references)
Recommended application cues
Catalog discovery cues, not supplier-verified claims.
Related HS Code / Compliance
Compliance cues are non-linked reference tags and require shipment review.